1-[(2-Bromophenyl)sulfonyl]-4-methyl-1H-imidazole(CAS: 951884-07-4)

The compound 1-[(2-Bromophenyl)sulfonyl]-4-methyl-1H-imidazole (CAS: 951884-07-4) is a crystalline solid with a molecular weight of approximately 346.05 g/mol. It has a low solubility in water but is soluble in organic solvents like methanol and ethanol. The compound is known for its reactivity towards nucleophiles and can undergo substitution reactions. It is not flammable but may decompose at high temperatures, releasing bromine and sulfur dioxide. It is also susceptible to hydrolysis in basic media.

1-[(2-Bromophenyl)sulfonyl]-4-methyl-1H-imidazole (CAS: 951884-07-4) can be synthesized via the coupling of 2-bromophenylsulfonyl isocyanate with 4-methylimidazole in the presence of a suitable catalyst such as 4-(dimethylamino)pyridine (DMAP). The reaction typically proceeds with high selectivity and good yield under mild conditions, making it a versatile synthetic route for this compound.

1-[(2-Bromophenyl)sulfonyl]-4-methyl-1H-imidazole (CAS: 951884-07-4) is used in various industries, including pharmaceuticals for the modification of drug molecules, and polymers for enhancing their thermal stability and other physical properties. It also finds applications in sensor technology, particularly in gas sensing devices, and in the electronics industry for its role in semiconductor materials.

When handling 1-[(2-Bromophenyl)sulfonyl]-4-methyl-1H-imidazole (CAS: 951884-07-4), it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place, away from heat and direct sunlight. Fume hoods should be used during handling to minimize exposure to bromine and sulfur dioxide. In case of a spill, it should be cleaned up immediately with appropriate absorbent materials, and the area should be well-ventilated. Always refer to the safety data sheet (SDS) for detailed handling and disposal information.