2-Methyl-2-propanyl [(2R)-1-oxo-2-propanyl]carbamate(CAS: 82353-56-8)

2-Methyl-2-propanyl [(2R)-1-oxo-2-propanyl]carbamate is a colorless liquid with a molecular weight of 136.19 g/mol. It melts at -35°C and boils at 126°C. Its solubility in water is low, and it is more soluble in organic solvents. Chemically, it is reactive towards nucleophiles and exhibits good stability under acidic conditions. It is used in organic synthesis and pharmaceutical applications.

2-Methyl-2-propanyl [(2R)-1-oxo-2-propanyl]carbamate is typically synthesized via a multistep process involving the reaction of 2-methyl-2-propanol with carbon dioxide in the presence of a chiral catalyst, such as (+)-10-camphorsulfonic acid, to achieve enantioselective formation. The product undergoes a carbamate formation step to generate the final compound.

2-Methyl-2-propanyl [(2R)-1-oxo-2-propanyl]carbamate is used primarily in the pharmaceutical industry for the synthesis of chiral compounds. It is also utilized in polymer chemistry for developing new materials, and in the production of sensors and semiconductors for their unique reactivity and stability.

When handling 2-Methyl-2-propanyl [(2R)-1-oxo-2-propanyl]carbamate, use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store it in a cool, dry place away from sources of heat and ignition. Handle it in a well-ventilated area or fume hood to avoid inhalation. In case of spill, use appropriate spill cleanup materials and consult a safety data sheet (SDS) for specific instructions. Follow standard laboratory safety protocols at all times.