2-Bromo-4-fluorothioanisole(CAS: 91524-70-8)

2-Bromo-4-fluorothioanisole (CAS: 91524-70-8) is a crystalline solid with a molecular weight of approximately 245.01 g/mol. It has a limited water solubility and is poorly soluble in common organic solvents like ethanol and acetone. The compound is known for its reactivity, particularly towards nucleophiles and electrophiles, and it can undergo bromination and thioether reactions.

2-Bromo-4-fluorothioanisole is typically synthesized via the bromination of 4-fluorothioanisole using bromine in the presence of pyridine as a base. The reaction is carried out in a solvent such as dichloromethane. The process involves the electrophilic attack of bromine on the anisole moiety, yielding a high yield of the desired product with good selectivity.

2-Bromo-4-fluorothioanisole (CAS: 91524-70-8) is primarily used in the pharmaceutical industry for the synthesis of complex organic compounds. It is also utilized in the polymer industry for the modification of polymer properties. Additionally, it has applications in the production of sensors and in semiconductor manufacturing processes related to material science.

When handling 2-Bromo-4-fluorothioanisole (CAS: 91524-70-8), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat to protect against skin and eye contact. Work should be conducted in a well-ventilated area or fume hood. In case of a spill, immediately clean up using appropriate cleaning agents and refer to the safety data sheet (SDS) for detailed instructions. Ensure proper storage in a cool, dry place away from oxidizing agents and other incompatible chemicals.