3-Bromo-4-hydroxy-5-methoxybenzaldehyde(CAS: 2973-76-4)

3-Bromo-4-hydroxy-5-methoxybenzaldehyde is a white crystalline solid with a molecular weight of approximately 276.07 g/mol. It has a solubility of about 1.5 g/L in water and is poorly soluble in most organic solvents. This compound is moderately reactive towards nucleophiles and can undergo substitution reactions. It has a pungent odor and can react with strong oxidizers and reductants.

3-Bromo-4-hydroxy-5-methoxybenzaldehyde can be synthesized via bromination of 4-hydroxy-5-methoxybenzaldehyde followed by hydrolysis. The synthesis typically involves the use of N-bromosuccinimide (NBS) as a brominating agent and a radical initiator in an organic solvent like dichloromethane. The reaction is carried out at room temperature and yields a product with high purity and selectivity.

3-Bromo-4-hydroxy-5-methoxybenzaldehyde is used in various industries. It finds applications in the pharmaceutical sector for the synthesis of certain drugs. It is also used in the production of sensors and as a precursor in the synthesis of dyes and other organic compounds. Additionally, it has some roles in the polymer industry for creating new materials with specific properties.

When handling 3-Bromo-4-hydroxy-5-methoxybenzaldehyde, proper personal protective equipment (PPE) should be worn, including gloves, safety goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to minimize exposure to its fumes. Spills should be cleaned up with caution, and appropriate spill clean-up procedures should be followed. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.