1-Methyl-1H-imidazole-2-carboxylic acid(CAS: 20485-43-2)

1-Methyl-1H-imidazole-2-carboxylic acid (CAS: 20485-43-2) is a white to off-white crystalline solid with a molecular weight of approximately 148.17 g/mol. It is sparingly soluble in water and ethanol. It exhibits moderate acidity and can react with bases to form salts. This compound is stable under normal conditions but reacts with strong oxidizers to produce gaseous products.

1-Methyl-1H-imidazole-2-carboxylic acid can be synthesized through the condensation of methyl isocyanate with imidazole, followed by hydrolysis. Commonly, a mild base is used as a catalyst, with a yield of up to 85%. The reaction is typically carried out in a solvent such as methanol or ethanol under mild conditions to ensure high selectivity.

1-Methyl-1H-imidazole-2-carboxylic acid (CAS: 20485-43-2) is utilized in various industries, including pharmaceuticals for drug synthesis, polymers for functional materials, and sensors for analytical applications. It is also used in the semiconductor industry as a precursor for metal organic compounds.

When handling 1-Methyl-1H-imidazole-2-carboxylic acid (CAS: 20485-43-2), it is important to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risk. Spills should be cleaned up using appropriate absorbents, and the area should be well-ventilated. Always consult the Safety Data Sheet (SDS) for detailed safety information.