4-Amino-2(1H)-pyrimidinethione(CAS: 333-49-3)

4-Amino-2(1H)-pyrimidinethione (CAS: 333-49-3) is a crystalline solid with a molecular weight of approximately 111.11 g/mol. It has a solubility of about 20 g/L in water. This compound is moderately reactive and can undergo substitution reactions. It is stable under normal conditions but should be stored away from strong acids and bases.

4-Amino-2(1H)-pyrimidinethione is typically synthesized via the amidation reaction of 2-aminothiazole with acetic anhydride. The reaction is catalyzed by a Lewis acid like aluminum chloride. The yield is usually around 80%, and the product is purified by recrystallization from water.

4-Amino-2(1H)-pyrimidinethione (CAS: 333-49-3) is primarily used in the pharmaceutical and agricultural industries. It acts as a precursor for the synthesis of various bioactive compounds and herbicides. Additionally, it is used in the polymer industry for the modification of polymer properties.

When handling 4-Amino-2(1H)-pyrimidinethione (CAS: 333-49-3),佩戴适当的个人防护装备，如手套和实验室外套。应在通风橱中操作以避免吸入蒸汽。如果发生泄漏，应立即使用适当的吸附材料清除，并确保良好的通风。参考安全数据表获取详细信息。