1-(2-Methylphenyl)ethanol(CAS: 7287-82-3)

1-(2-Methylphenyl)ethanol is a colorless liquid with a molecular weight of approximately 130.21 g/mol. It has a pKa of around 15.3 and a boiling point of 175-176°C. The compound is slightly soluble in water but miscible with organic solvents. It is reactive towards acids and bases, and can undergo esterification and oxidation reactions.

1-(2-Methylphenyl)ethanol is commonly synthesized by the hydroxylation of 2-methylbenzyl chloride using a phase-transfer catalyst like tetrabutylammonium hydroxide. This method provides good selectivity and yield. Other methods include the reduction of 2-methylbenzaldehyde using lithium aluminum hydride or other reducing agents.

1-(2-Methylphenyl)ethanol finds applications in the pharmaceutical industry as an intermediate in the synthesis of various drugs. It is also used in the manufacturing of fragrances and perfumes, as well as in the production of certain polymers and resins. Additionally, it is utilized in the development of sensors and in semiconductor applications.

When handling 1-(2-Methylphenyl)ethanol (CAS: 7287-82-3), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure the area is well-ventilated and work in a fume hood. Spills should be cleaned up promptly using absorbent materials, and disposal should follow local regulations. Always consult the Safety Data Sheet (SDS) for detailed information and guidelines.