3-Amino-N-isopropylbenzamide(CAS: 81882-62-4)

3-Amino-N-isopropylbenzamide (CAS: 81882-62-4) is a crystalline compound with a molecular weight of approximately 217.26 g/mol. It has a pKa of around 9.4 and is moderately soluble in water. The compound is known for its low reactivity under normal conditions but can undergo hydrolysis in alkaline solutions. It exhibits good solubility in polar solvents such as ethanol and acetone.

3-Amino-N-isopropylbenzamide is typically synthesized via a multi-step process. It involves the coupling of isopropylbenzoic acid with aniline using a Lewis acid catalyst such as aluminum chloride. The reaction is carried out in a suitable solvent like dichloromethane. The yield is around 85-90%, and the process is selective and efficient under mild conditions.

3-Amino-N-isopropylbenzamide (CAS: 81882-62-4) is used in various industries. It is a key intermediate in the pharmaceutical industry, where it serves as a building block for synthesizing drugs. It is also utilized in the production of dyes and pigments in the chemical industry. Additionally, it can be used in the development of sensors and electronic materials in the semiconductor industry.

When handling 3-Amino-N-isopropylbenzamide (CAS: 81882-62-4), it is important to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight and sources of heat. In case of a spill, immediately clean it up using appropriate absorbents and dispose of the waste according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for specific safety information.