N-Tetradecanoyl-L-phenylalanine(CAS: 68792-49-4)

N-Tetradecanoyl-L-phenylalanine (CAS: 68792-49-4) is a white crystalline solid with a molecular weight of approximately 314.41 g/mol. It has low water solubility but is soluble in organic solvents. This compound exhibits moderate reactivity, particularly in esterification reactions. It crystallizes in the monoclinic system with a specific melting point of about 150°C. It is stable under normal conditions but should be protected from moisture and heat.

N-Tetradecanoyl-L-phenylalanine (CAS: 68792-49-4) is typically synthesized via a solid-phase peptide synthesis (SPPS) method. The reaction involves the coupling of tetradecanoic acid with L-phenylalanine using standard peptide coupling reagents like Fmoc (fluorenylmethoxycarbonyl) chemistry. The process yields a high purity product with good selectivity and yield, typically above 90%, depending on the specific conditions.

N-Tetradecanoyl-L-phenylalanine (CAS: 68792-49-4) is used in several industries, including pharmaceuticals for the development of peptides and drug delivery systems, and in polymer science for the modification of polymers with biocompatible functionalities. It also finds applications in the production of sensors and semiconductors, where its specific chemical and physical properties are beneficial.

When handling N-Tetradecanoyl-L-phenylalanine (CAS: 68792-49-4), it is important to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up immediately using appropriate absorbents and waste should be disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.