Gemcitabine(CAS: 95058-81-4)

Gemcitabine is a chemotherapy drug with the chemical formula C9H14N2O4. It is a nucleoside analog used to treat various cancers, including pancreatic, lung, and breast cancer. Gemcitabine works by inhibiting DNA synthesis, thereby slowing or stopping the growth of cancer cells. It is commonly available as a white crystalline powder and is known for its solubility in water and DMSO.

Gemcitabine is primarily used in oncology to treat solid tumors such as pancreatic, non-small cell lung, and breast cancers. It is also employed in combination therapy for bladder cancer and has been researched for use in other malignancies. As a nucleoside analog, Gemcitabine is effective in disrupting DNA replication in rapidly dividing cells, making it a key component in cancer treatment protocols.

Gemcitabine is generally considered safe when used under medical supervision, but it can cause side effects such as nausea, fatigue, and myelosuppression. Proper handling and administration are essential to minimize risks. Safety standards for Gemcitabine are well-established, and it is classified as a chemotherapy agent with specific precautions for healthcare professionals and patients.

Gemcitabine should be stored in a cool, dry place away from direct light. It is typically kept at a temperature between 2°C to 8°C and requires protection from moisture. The compound is usually stored in a sealed container to maintain its stability and potency over time.