(1R)-1-(4-ethoxyphenyl)ethan-1-ol(CAS: 225920-04-7)

(1R)-1-(4-ethoxyphenyl)ethan-1-ol is a clear, colorless liquid with a molecular weight of 194.23 g/mol. It has a high solubility in ethanol and acetone but is only slightly soluble in water. This compound is known for its reactivity towards nucleophiles and its ability to undergo various reactions such as esterification and alkylation. It crystallizes in the form of colorless crystals at low temperatures.

(1R)-1-(4-ethoxyphenyl)ethan-1-ol can be synthesized via a two-step process. In the first step, phenol is converted to 4-ethoxyphenol using ethyl bromide and potassium tert-butoxide as reagents. In the second step, 4-ethoxyphenol is treated with ethyl bromide and potassium tert-butoxide to form the desired compound. This process typically yields 80-85% purity with excellent selectivity.

(1R)-1-(4-ethoxyphenyl)ethan-1-ol is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the polymer industry for the production of speciality polymers. Additionally, it is used in the fragrance industry as a precursor for the synthesis of various scent compounds and in sensors for its ability to detect certain chemicals.

When handling (1R)-1-(4-ethoxyphenyl)ethan-1-ol, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a laboratory coat. Ensure the use of a fume hood during operations to minimize inhalation exposure. In case of a spill, immediately clean up using appropriate absorbents and dispose of the waste according to local regulations. Refer to the Safety Data Sheet (SDS) for specific safety information and procedures.