5-Methyl-2-(1H-pyrrol-1-yl)aniline(CAS: 59194-21-7)

5-Methyl-2-(1H-pyrrol-1-yl)aniline is a solid with a crystalline form. Its molecular weight is approximately 229.26 g/mol. The compound is moderately soluble in water and ethanol. It is reactive toward oxidizing agents. It has a pKa of about 7.2 and exhibits basic properties. This compound is commonly used in organic synthesis and chemical reagents.

5-Methyl-2-(1H-pyrrol-1-yl)aniline can be synthesized via a multistep process involving the condensation of 2-chloro-5-methylaniline with pyrrole. Commonly, this reaction is catalyzed by a strong base such as sodium hydride. The yield is around 70-80%, and the purity can be enhanced by recrystallization.

5-Methyl-2-(1H-pyrrol-1-yl)aniline is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the production of dyes, sensors, and semiconductors. Its use in polymers is less common but still significant for specific applications.

When handling 5-Methyl-2-(1H-pyrrol-1-yl)aniline, it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety glasses. Fume hoods should be used during operations. Spills should be cleaned up with care, using absorbent materials, and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.