Sodium 1,2-dioleoyl-sn-glycero-3-phospho-L-serine(CAS: 90693-88-2)

Sodium 1,2-dioleoyl-sn-glycero-3-phospho-L-serine is a white to off-white crystalline powder. Its molecular weight is approximately 771.9 g/mol. It has low solubility in water but is soluble in organic solvents like chloroform and methanol. It is relatively stable under normal conditions but can be sensitive to strong acids and bases. It reacts with water to form the corresponding free acid and sodium hydroxide.

Sodium 1,2-dioleoyl-sn-glycero-3-phospho-L-serine is synthesized by the amide coupling of dioleoyl-sn-glycero-3-phosphocholine with L-serine in the presence of a catalyst such as triethylamine. The reaction typically proceeds with good yield and selectivity, and the product is isolated by recrystallization from an appropriate solvent.

Sodium 1,2-dioleoyl-sn-glycero-3-phospho-L-serine is used in the pharmaceutical industry for its role as a phospholipid component in drug delivery systems and as a model membrane component. It is also utilized in the polymer industry for its ability to improve material properties. Additionally, it is used in sensors and semiconductors due to its amphiphilic nature and potential for self-assembly.

When handling Sodium 1,2-dioleoyl-sn-glycero-3-phospho-L-serine, use appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Store it in a cool, dry place away from direct sunlight and heat sources. Handle it in a well-ventilated area or fume hood to minimize inhalation risks. In case of spill, neutralize with an appropriate acid-base reagent and dispose of the material according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed guidelines.