3-Methyl-1,3-dihydro-2H-imidazo[4,5-f]quinolin-2-one(CAS: 144486-08-8)

3-Methyl-1,3-dihydro-2H-imidazo[4,5-f]quinolin-2-one is a crystalline solid with a molecular weight of approximately 221.21 g/mol. It has a low solubility in water but is soluble in common organic solvents like ethanol and acetone. This compound is moderately reactive, particularly towards nucleophiles and electrophiles. It is stable under normal conditions but should be stored in a dry, cool place away from moisture and direct sunlight.

3-Methyl-1,3-dihydro-2H-imidazo[4,5-f]quinolin-2-one can be synthesized via a multi-step process involving amination and cyclization reactions. Commonly, an imidazopyridine derivative undergoes amination with methylamine followed by a cyclization step. The reaction conditions typically involve the use of a Lewis acid catalyst and are conducted under mild conditions to achieve high selectivity and yield.

3-Methyl-1,3-dihydro-2H-imidazo[4,5-f]quinolin-2-one is primarily used in the pharmaceutical industry for the development of new drugs, particularly in anti-inflammatory and anticancer research. It also finds applications in the semiconductor industry as a dopant material and in the production of certain types of polymers and sensors.

When handling 3-Methyl-1,3-dihydro-2H-imidazo[4,5-f]quinolin-2-one, it is crucial to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize exposure to the compound. In case of a spill, immediately clean it up using appropriate absorbent materials and dispose of the waste according to local regulations. Always refer to the safety data sheet (SDS) for detailed information on safe handling and disposal.