(2,6-Dimethyl-4-pyridinyl)boronic acid(CAS: 846548-44-5)

(2,6-Dimethyl-4-pyridinyl)boronic acid has a crystalline form with a molecular weight of approximately 167.23 g/mol. It has low solubility in water but is more soluble in organic solvents like methanol and ethanol. This compound exhibits good reactivity in boronate ester formation and is often used in organoboron chemistry and catalytic reactions.

(2,6-Dimethyl-4-pyridinyl)boronic acid is typically synthesized through the reaction of 2,6-dimethylpyridine with an organoboronic acid. Common catalysts include palladium(II) acetate and triphenylphosphine. The reaction yields a boronic ester with high selectivity and good yield under mild conditions.

(2,6-Dimethyl-4-pyridinyl)boronic acid is widely used in the pharmaceutical industry for drug synthesis, particularly in asymmetric synthesis and catalytic reactions. It is also used in the polymer industry for functionalization and in the electronics industry for semiconductor applications and sensor technology.

When handling (2,6-Dimethyl-4-pyridinyl)boronic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety glasses. Store it in a fume hood to avoid inhalation of dust. In case of a spill, clean it up using appropriate procedures and refer to the Safety Data Sheet (SDS) for detailed instructions. Always work in a well-ventilated area and follow laboratory safety guidelines.