1-(4-Bromophenyl)ethanone(CAS: 99-90-1)

1-(4-Bromophenyl)ethanone (CAS: 99-90-1) is a white crystalline solid with a molecular weight of approximately 211.02 g/mol. It is poorly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is relatively stable but can undergo bromine displacement reactions under basic conditions. It has a melting point of 78-79°C and a boiling point of 224°C. It is also reactive towards nucleophiles and can participate in electrophilic aromatic substitution reactions.

1-(4-Bromophenyl)ethanone (CAS: 99-90-1) is commonly synthesized via bromination of benzyl alcohol with bromine in the presence of a Lewis acid catalyst like aluminum triflate. The reaction proceeds with high selectivity to the ortho position, yielding a high yield of the desired product. The process requires careful control of reaction conditions to achieve optimal results.

1-(4-Bromophenyl)ethanone (CAS: 99-90-1) is used in the pharmaceutical industry for the synthesis of various organic compounds. It also finds application in the polymer industry as a monomer, in the sensor industry for gas detection, and in the semiconductor industry for chemical vapor deposition (CVD) processes. Its use in these industries highlights its importance in chemical synthesis and material science.

When handling 1-(4-Bromophenyl)ethanone (CAS: 99-90-1), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Ensure the use of fume hoods to minimize exposure to the vapors. Store in a cool, dry place away from heat and sources of ignition. In the event of a spill, use appropriate containment and disposal methods as outlined in the safety data sheet (SDS). Always follow proper laboratory safety protocols and consult the SDS for specific handling instructions.