(1R)-1-Phenyl-1,2-ethanediol(CAS: 16355-00-3)

(1R)-1-Phenyl-1,2-ethanediol is a colorless liquid with a molecular weight of approximately 148.22 g/mol. It has a low melting point and is moderately soluble in water. It reacts with carboxylic acids to form esters and can be used in organic synthesis. It is also known for its use in the production of polyurethane and as a precursor in the synthesis of other organic compounds.

(1R)-1-Phenyl-1,2-ethanediol can be synthesized through the reduction of 1-phenyl-1,2-ethanone using hydrogen and a catalyst such as palladium on carbon. The reaction is carried out under mild conditions to achieve good yield and selectivity. This method is commonly employed in the pharmaceutical and polymer industries.

(1R)-1-Phenyl-1,2-ethanediol is used in various industries, including pharmaceuticals, where it serves as a precursor for drug synthesis, and in the production of polyurethane for use in coatings and insulation. It is also utilized in the manufacture of certain types of plastic and in the development of sensors and semiconductors.

When handling (1R)-1-Phenyl-1,2-ethanediol, it is important to use appropriate personal protective equipment (PPE), including gloves and safety goggles. This compound should be used in a well-ventilated area or fume hood to minimize exposure. In case of spill, it should be handled carefully, and appropriate spill cleanup procedures should be followed. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.