5,8-Dimethoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-amine(CAS: 219715-62-5)

5,8-Dimethoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-amine is a crystalline solid with a molecular weight of approximately 280.21 g/mol. It has a limited solubility in water and is more soluble in organic solvents like methanol and ethanol. This compound is known for its low reactivity under normal conditions, but it can be sensitive to strong acids and bases. It does not decompose easily, but prolonged exposure to heat may lead to ring-opening reactions.

5,8-Dimethoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-amine can be synthesized through a multi-step process involving the protection of a pyrimidine ring, followed by the introduction of nitro and methoxy groups using appropriate reagents. The synthesis typically requires the use of catalysts such as palladium or iron to facilitate the coupling reactions. The yield of the final product is generally around 70-80%, with good selectivity towards the desired product.

5,8-Dimethoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-amine is primarily used in the pharmaceutical industry for its potential as an anticancer agent. It also finds applications in the field of organic electronics, particularly in the development of organic semiconductors and sensors. This compound may also be used in polymer chemistry as a functional monomer or in the preparation of other complex organic molecules.

When handling 5,8-Dimethoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-amine, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, it is recommended to use appropriate spill kits and to ventilate the area. For more detailed safety information, always consult the Safety Data Sheet (SDS) associated with this chemical.