2-Ethoxybenzaldehyde(CAS: 613-69-4)

2-Ethoxybenzaldehyde (CAS: 613-69-4) is a crystalline compound with a molecular weight of approximately 150.22 g/mol. It has a pKa of around 15.8. Solubility in water is low, approximately 0.36 g/100 mL at 25°C, but it is soluble in organic solvents like ethanol and acetone. The compound is moderately reactive, especially towards nucleophiles and reducing agents.

2-Ethoxybenzaldehyde (CAS: 613-69-4) can be synthesized via the acylation of 2-ethoxybenzene with acetyl chloride in the presence of an acid catalyst like aluminum trichloride. The reaction is carried out under anhydrous conditions to ensure high yield and selectivity. Alternatively, it can be prepared by the reduction of 2-acetylphenol using sodium borohydride as a reducing agent.

2-Ethoxybenzaldehyde (CAS: 613-69-4) finds applications in various industries. It is used as a key intermediate in the synthesis of several pharmaceuticals, particularly pain relievers and anti-inflammatory drugs. It also serves as a precursor in the production of certain polymers and is utilized in the formulation of fragrances and flavorings. Additionally, it can be employed in the development of sensors and as a semiconductor material.

When handling 2-Ethoxybenzaldehyde (CAS: 613-69-4), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Use a fume hood during operations to minimize exposure to the compound. Ensure proper ventilation and avoid skin contact and inhalation. In case of a spill, neutralize with an appropriate solution and dispose of the waste following local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.