Pivaloylacetonitrile(CAS: 59997-51-2)

Pivaloylacetonitrile (CAS: 59997-51-2) is a colorless liquid with a molecular weight of approximately 152.16 g/mol. It has a melting point of 2-4°C and a boiling point of 109-111°C. The compound is soluble in common organic solvents such as ethanol and acetone. It is moderately reactive, especially towards nucleophiles and bases.

Pivaloylacetonitrile can be synthesized by the nitrilation of pivaloyl chloride with an aqueous sodium hydroxide solution, followed by acidification. Common catalysts include sodium hydroxide, and the reaction typically yields a product with high selectivity and good yield.

Pivaloylacetonitrile (CAS: 59997-51-2) is used in the pharmaceutical industry for the synthesis of certain organic compounds, and in the polymer industry for functional materials. It also has potential applications in sensor technology and the production of semiconductors.

When handling Pivaloylacetonitrile, it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety glasses. The compound should be stored in a cool, dry place away from heat sources and incompatible materials. In case of a spill, it should be cleaned up using appropriate methods, and the area should be well-ventilated. A Safety Data Sheet (SDS) should be consulted for detailed safety information.