5-Bromo-1,3-dihydroisobenzofuran(CAS: 220513-49-5)

5-Bromo-1,3-dihydroisobenzofuran (CAS: 220513-49-5) is a crystalline solid with a molecular weight of approximately 210.03 g/mol. It has a low water solubility but is soluble in common organic solvents like dichloromethane and acetonitrile. This compound exhibits moderate reactivity, particularly towards nucleophilic substitution reactions at the bromine substituent.

5-Bromo-1,3-dihydroisobenzofuran is typically synthesized via a bromination reaction of 1,3-dihydroisobenzofuran using bromine in the presence of a Lewis acid catalyst, such as aluminum bromide. The reaction is carried out under anhydrous conditions to achieve high yield and selectivity.

5-Bromo-1,3-dihydroisobenzofuran (CAS: 220513-49-5) is used in various industries, including pharmaceuticals, where it serves as a building block for drug synthesis, and in the manufacturing of semiconductors due to its electronic properties. It also finds use in the development of sensors and polymers.

When handling 5-Bromo-1,3-dihydroisobenzofuran (CAS: 220513-49-5), proper personal protective equipment (PPE) such as gloves, safety goggles, and a laboratory coat should be worn. This compound should be used in a fume hood to minimize exposure. Spills should be handled carefully, and the appropriate safety data sheet (SDS) should be consulted for detailed instructions.