2,4-Dichloro-1,3-thiazole-5-carbonitrile(CAS: 82554-18-5)

2,4-Dichloro-1,3-thiazole-5-carbonitrile is a white crystalline solid with a molecular weight of approximately 210.03 g/mol. It has low water solubility but good solubility in organic solvents. This compound is known for its low reactivity under normal conditions, but it may react with strong bases or metal catalysts. It is stable under normal storage conditions but should be protected from strong acids.

2,4-Dichloro-1,3-thiazole-5-carbonitrile is typically synthesized via the reaction of 2,4-dichlorothiazole with cyanate esters. This process can be conducted in the presence of a suitable base or catalyst to improve yield and selectivity. The reaction is performed under mild conditions to avoid decomposition of the product.

2,4-Dichloro-1,3-thiazole-5-carbonitrile has applications in the pharmaceutical industry for use as an intermediate in the synthesis of certain drugs. It is also used in the polymer industry for the production of advanced materials. Additionally, it plays a role in the development of sensors and as a component in semiconductor processes.

When handling 2,4-Dichloro-1,3-thiazole-5-carbonitrile, it is important to wear appropriate personal protective equipment (PPE) including gloves, safety glasses, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. In case of spill, avoid contact with water and clean up using absorbent materials. For detailed safety information, refer to the Safety Data Sheet (SDS).