6-chloro-7-methyl-2,3,4,9-tetrahydro-1H-fluorene-1-carboxamide;6-chloro-8-methyl-2,3,4,9-tetrahydro-1H-fluorene-1-carboxamide;6-methyl-2,3,4,9-tetrahydro-1H-fluorene-1-carboxamide(CAS: 9005-71-4)

6-Chloro-7-methyl-2,3,4,9-tetrahydro-1H-fluorene-1-carboxamide is a white crystalline powder with a molecular weight of approximately 275.8 g/mol. It has a solubility of about 0.5 g/L in water and is sparingly soluble in common organic solvents. This compound is relatively stable under normal conditions but can react with strong bases to form the corresponding amine. It is used in various applications due to its structural properties.

This compound can be synthesized via a multi-step process involving the chlorination of a precursor compound, followed by the methylation and subsequent amidation reactions. Commonly, the synthesis involves the use of chloromethylating agents and methylating reagents, with high selectivity and good yields under optimized reaction conditions. The exact method can vary based on the specific starting material and desired purity.

6-Chloro-7-methyl-2,3,4,9-tetrahydro-1H-fluorene-1-carboxamide is primarily used in the pharmaceutical and chemical industries for the development of certain drugs and intermediates. It also finds applications in the production of polymers, sensors, and semiconductors due to its unique structural properties and reactivity.

When handling 6-chloro-7-methyl-2,3,4,9-tetrahydro-1H-fluorene-1-carboxamide, it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up with caution, using appropriate absorbent materials, and the area should be thoroughly rinsed. Refer to the Safety Data Sheet (SDS) for more detailed information on handling and storage.