N-(7H-Purin-6-yl)benzamide(CAS: 4005-49-6)

N-(7H-Purin-6-yl)benzamide (CAS: 4005-49-6) is a white crystalline solid with a molecular weight of approximately 246.23 g/mol. It is slightly soluble in water and ethanol but more soluble in organic solvents like dichloromethane. Chemically, it is stable under normal conditions but reacts with acids to form a free base. It is often used in pharmaceutical applications due to its stability and reactivity.

N-(7H-Purin-6-yl)benzamide (CAS: 4005-49-6) can be synthesized by reacting 6-aminopurine with benzoyl chloride in the presence of a base like triethylamine. The reaction is typically carried out in anhydrous dichloromethane under room temperature conditions. The yield is around 70-80%, and the product is isolated by recrystallization from ethanol.

N-(7H-Purin-6-yl)benzamide (CAS: 4005-49-6) is primarily used in the pharmaceutical industry for its potential as an antiviral and antifungal agent. It is also utilized in the synthesis of other purine derivatives and in research applications for its structural similarity to purine bases.

When handling N-(7H-Purin-6-yl)benzamide (CAS: 4005-49-6), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbents, and the area should be thoroughly washed down with water. Refer to the Safety Data Sheet (SDS) for detailed safety and handling instructions.