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2-Bromo-1,3-difluoro-5-methoxybenzene(CAS: 202865-61-0)

2-Bromo-1,3-difluoro-5-methoxybenzene
CAS Number

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Basic Information

Molecular Formula
C7H5BrF2O
Molecular Weight
223.02 g/mol

Physical Properties

Melting Point
25-29°C
Boiling Point
176.5±35.0 °C at 760 mmHg
Flash Point
72.6±10.2 °C
Water Solubility
Insoluble in water.

Chemical Identifiers

SMILES
COC1=CC(=C(C(=C1)F)Br)F
InChIKey
GEJMNTXYFBBTFH-UHFFFAOYSA-N

Database References

MDL Number
MFCD00143268

FAQ

2-Bromo-1,3-difluoro-5-methoxybenzene is a crystalline compound with a molecular weight of approximately 262.04 g/mol. It has a low solubility in water but is more soluble in organic solvents like acetone and ethanol. Chemically, it is relatively stable but can react with strong nucleophiles. The compound is used in organic synthesis and pharmaceuticals.
2-Bromo-1,3-difluoro-5-methoxybenzene is synthesized via a halogenation reaction of 1,3-difluoro-5-methoxybenzene with bromine in the presence of a Lewis acid catalyst. The reaction is typically performed under anhydrous conditions to achieve good yield and selectivity.
2-Bromo-1,3-difluoro-5-methoxybenzene is used in the pharmaceutical industry for the synthesis of certain drugs due to its functional groups. It is also utilized in organic synthesis for the preparation of other aromatic compounds and in the polymer industry for the development of advanced materials.
When handling 2-Bromo-1,3-difluoro-5-methoxybenzene, ensure the use of appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood. Follow standard laboratory safety procedures and have a safety data sheet (SDS) readily available for reference in case of spills or accidents.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

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