Methyl 3-fluoro-4-nitrobenzoate(CAS: 185629-31-6)

Methyl 3-fluoro-4-nitrobenzoate (CAS: 185629-31-6) is a crystalline solid at room temperature with a molecular weight of approximately 228.09 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. The compound is moderately reactive, particularly towards reducing agents and bases. It exhibits a characteristic melting point and is stable under normal storage conditions.

Methyl 3-fluoro-4-nitrobenzoate is typically synthesized via the esterification of 3-fluoro-4-nitrobenzoic acid with methanol in the presence of acetic acid as a catalyst. The reaction is carried out under mild conditions with a yield of around 85%. Other methods include the nitration of 3-fluorobenzoic acid followed by esterification, providing high selectivity and yield.

Methyl 3-fluoro-4-nitrobenzoate (CAS: 185629-31-6) is used in the pharmaceutical industry for the synthesis of certain intermediates and as a reagent in organic synthesis. It is also utilized in the polymer industry for the production of functional polymers and in the sensor industry for the development of chemical sensors. Other applications include use in semiconductors for specific chemical treatments.

When handling Methyl 3-fluoro-4-nitrobenzoate (CAS: 185629-31-6), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or a fume hood. Spills should be cleaned up promptly using appropriate absorbent materials. Safety data sheets (SDS) should be consulted for detailed emergency procedures and storage recommendations.