5-Chloro-2-methyl-3-pyridinecarboxylic acid(CAS: 1092286-30-0)

5-Chloro-2-methyl-3-pyridinecarboxylic acid is a white crystalline solid with a molecular weight of approximately 190.59 g/mol. It is slightly soluble in water and ethanol. The compound is moderately reactive, particularly with strong bases and nucleophiles. It is used in organic synthesis and as an intermediate in various chemical processes.

5-Chloro-2-methyl-3-pyridinecarboxylic acid is typically synthesized through the bromination of 2-methyl-3-pyridine carboxylic acid, followed by the displacement of bromine with chlorine. The reaction involves the use of a suitable base and can achieve a yield of up to 85%. The product can be purified by recrystallization.

5-Chloro-2-methyl-3-pyridinecarboxylic acid is primarily used in the pharmaceutical and chemical industries as an intermediate for the synthesis of other compounds. It is also used in the production of polymers and sensors due to its specific chemical properties.

When handling 5-Chloro-2-methyl-3-pyridinecarboxylic acid, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight. In case of a spill, it should be handled with care and cleaned up using appropriate safety measures. For detailed safety information, refer to the Safety Data Sheet (SDS).