Adavosertib(CAS: 955365-80-7)

Adavosertib is a small molecule CDK1/2 inhibitor with the chemical formula C19H21N5O3S. It is a white to off-white powder, highly soluble in DMSO, and exhibits stability under normal laboratory conditions. Adavosertib is primarily used in cancer research and therapy, targeting cell cycle regulation by inhibiting cyclin-dependent kinases.

Adavosertib (CAS: 955365-80-7) is mainly used in pharmaceutical research for cancer treatment, particularly in clinical trials for solid tumors and hematological malignancies. It also serves as a tool compound in biochemical studies to investigate cell cycle mechanisms and kinase inhibition pathways.

Adavosertib is generally considered safe when handled properly, but it requires caution during use. Safety data indicates potential toxicity via inhalation or skin contact, so protective measures like gloves and ventilation are recommended. Regulatory bodies such as the FDA are evaluating its safety profile for therapeutic applications.

Adavosertib should be stored in a cool, dry place (15-25°C), protected from light, and kept in a sealed container to maintain stability. For long-term storage, refrigeration (2-8°C) is advised. Avoid exposure to moisture and ensure proper labeling to prevent contamination.