2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl L-valinate(CAS: 124832-26-4)

2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl L-valinate is a white crystalline solid with a molecular weight of approximately 367.35 g/mol. It is slightly soluble in water and has a pKa of 10.0. The compound is reactive towards nucleophiles and can undergo nucleophilic substitution reactions.

2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl L-valinate is synthesized via a multi-step process involving the coupling of L-valine with 2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethanoyl chloride, followed by a nucleophilic substitution reaction. The process typically involves the use of catalytic amounts of a suitable base and occurs with good yield and high selectivity.

2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl L-valinate is primarily used in the pharmaceutical industry for developing drug candidates. It is also utilized in the polymer industry for modifying polymer properties and in the sensor industry for developing biosensors.

When handling 2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl L-valinate, it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood. In case of a spill, immediately clean up with appropriate absorbent materials and follow the safety data sheet (SDS) guidelines for disposal.