4,5-Dicaffeoylquinic acid(CAS: 57378-72-0)

4,5-Dicaffeoylquinic acid is a crystalline compound with a molecular weight of approximately 508.17 g/mol. It has a low solubility in water but is more soluble in ethanol and methanol. Chemically, it is relatively stable but can undergo hydrolysis under alkaline conditions. This compound shows moderate reactivity towards acid-catalyzed cleavage and is sensitive to strong acids and bases.

4,5-Dicaffeoylquinic acid is typically synthesized through the esterification of quinic acid with 4,5-dicaffeoyl-CoA, catalyzed by lipases. The synthesis involves a multi-step process including esterification, purification, and crystallization. The yield is generally around 70-80%, and the method provides good selectivity for the desired product.

4,5-Dicaffeoylquinic acid finds applications in the pharmaceutical industry for its potential anti-inflammatory and antioxidant properties. It is also used in the food industry as a natural preservative and flavor enhancer. Additionally, it has applications in the cosmetic industry due to its potential skin-protecting effects and in the polymer industry for its antioxidant properties.

When handling 4,5-Dicaffeoylquinic acid, it is important to use appropriate personal protective equipment (PPE), including gloves and lab coats, to prevent skin contact. Store it in a cool, dry place, away from direct sunlight and heat sources. Use a fume hood during handling to minimize inhalation risk. In case of a spill, immediately clean up the area and consult the safety data sheet (SDS) for proper disposal procedures.