(6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid(CAS: 147511-69-1)

(6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid is a white to off-white crystalline solid with a molecular weight of approximately 429.36 g/mol. It has a pKa of about 2.5 and is sparingly soluble in water but more readily soluble in organic solvents. It is not particularly reactive under normal conditions but can undergo hydrolysis. This compound is typically stable but should be stored away from moisture and heat to prevent degradation.

(6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid can be synthesized through a multi-step process involving condensation reactions, ring formation, and hydroxylation. Commonly used catalysts include transition metals like palladium or platinum. The yield is typically around 70-80%, and the selectivity is good, providing a high purity product. This synthesis should be carried out under inert atmosphere to avoid decomposition.

(6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid is primarily used in the pharmaceutical industry for the development of potential therapeutic agents. It has shown promise in various biological assays and may be used as a precursor for further medicinal chemistry work. Additionally, it could have applications in polymer science and material science, particularly in the development of new materials with specific functional properties.

When handling (6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be managed carefully, and the area should be cleaned with appropriate solvents. Refer to the Safety Data Sheet (SDS) for specific handling instructions and emergency procedures. This compound is not particularly hazardous but should be treated with care to prevent accidental exposure or contamination.