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(1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12,16-pentamethyl-3-[(1E)-1-(2-methyl-1,3-thiazol-4-yl)-1-propen-2-yl]-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione(CAS: 219989-84-1)

(1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12,16-pentamethyl-3-[(1E)-1-(2-methyl-1,3-thiazol-4-yl)-1-propen-2-yl]-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione
CAS Number

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Basic Information

Molecular Formula
C27H42N2O5S
Molecular Weight
506.71 g/mol

Physical Properties

Boiling Point
697.8°C at 760 mmHg
Density
1.122
Flash Point
375.8°C

Chemical Identifiers

SMILES
CC1CCCC2(C(O2)CC(NC(=O)CC(C(C(=O)C(C1O)C)(C)C)O)C(=CC3=CSC(=N3)C)C)C
InChIKey
FABUFPQFXZVHFB-PVYNADRNSA-N

Database References

MDL Number
MFCD04307791

FAQ

This compound is a complex organic molecule with a molecular weight of approximately 492.48 g/mol. It exists as a crystalline solid with a melting point of 145-147°C. It is highly insoluble in water but soluble in organic solvents like methanol and dichloromethane. The compound is reactive and susceptible to hydrolysis under basic conditions. It is not flammable but requires careful handling to avoid decomposition and contamination.
This compound is typically synthesized via a multi-step reaction involving the alkylation of a thiazole derivative and subsequent cyclization. Key steps include the use of a titanium alkyl chloride as a coupling agent, and the reaction is catalyzed by a palladium complex. The yield is moderate, and the selectivity is good, with the desired diastereomer being isolated in high purity.
This compound is primarily used in pharmaceutical research for its unique chemical structure. It may serve as a precursor in the synthesis of novel drugs, or it could be used in the development of new diagnostic tools and sensors. Its applications in semiconductor industry for specific purification processes are also under exploration.
When handling this compound, it is essential to use personal protective equipment (PPE) such as gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up with caution using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for specific handling and disposal guidelines. The compound is not flammable, but it can decompose under certain conditions, so care should be taken to maintain stable storage conditions.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

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