Sodium 3-pyridinolate(CAS: 52536-09-1)

Sodium 3-pyridinolate (CAS: 52536-09-1) is a crystalline solid with a molecular weight of approximately 132.14 g/mol. It has a solubility of about 21.5 g/100 mL in water at room temperature. The compound is known for its good solubility in organic solvents such as ethanol and acetone. It is relatively stable under normal conditions but can react with acids to form pyridine. It is used as a ligand in coordination chemistry.

Sodium 3-pyridinolate can be synthesized by reacting 3-pyridinecarboxaldehyde with sodium hydroxide. The reaction is typically carried out in ethanol or methanol, yielding a 1:1 complex with a high yield. The process involves an Aldol condensation followed by salt formation. This method is preferred due to its simplicity and reproducibility.

Sodium 3-pyridinolate (CAS: 52536-09-1) is primarily used in the pharmaceutical industry as a chelating agent and as a ligand in coordination chemistry. It is also used in the synthesis of organic semiconductors and as a sensor component in analytical chemistry. Its use in polymers and other advanced materials is also being explored due to its unique chemical properties.

When handling Sodium 3-pyridinolate (CAS: 52536-09-1), it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. This compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. In the event of a spill, it should be cleaned up carefully while wearing PPE. Always refer to the Safety Data Sheet (SDS) for specific handling and emergency procedures.