1-{(E)-2-(Methylsulfanyl)-1-[2-(pentyloxy)phenyl]vinyl}-1H-imidazole(CAS: 130726-68-0)

1-{(E)-2-(Methylsulfanyl)-1-[2-(pentyloxy)phenyl]vinyl}-1H-imidazole is a solid compound with a molecular weight of approximately 413.5 g/mol. It has a moderate solubility in organic solvents like methanol and ethanol but is poorly soluble in water. The compound exhibits basic properties due to the imidazole ring, making it slightly basic in aqueous solutions. It is not highly reactive but can undergo substitution reactions under certain conditions.

1-{(E)-2-(Methylsulfanyl)-1-[2-(pentyloxy)phenyl]vinyl}-1H-imidazole is synthesized by reacting 2-(pentyloxy)phenylacetylene with 2-methylthiopropanol followed by imidization. This involves a multi-step process, including alkyne coupling and subsequent imidization with an appropriate imidizing agent. The reaction is typically carried out under mild conditions with a catalyst to ensure selectivity and high yield.

1-{(E)-2-(Methylsulfanyl)-1-[2-(pentyloxy)phenyl]vinyl}-1H-imidazole is used in the pharmaceutical industry for its potential as a drug candidate. It is also explored in the sensor industry due to its chemical reactivity and selectivity. Additionally, it shows promise in environmental sensing applications, particularly in detecting specific gases and chemicals.

When handling 1-{(E)-2-(Methylsulfanyl)-1-[2-(pentyloxy)phenyl]vinyl}-1H-imidazole, it is important to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Ensure the work is conducted in a well-ventilated area or a fume hood to avoid inhalation of any vapors. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.