2-Acetylcyclohexanone(CAS: 874-23-7)

2-Acetylcyclohexanone (CAS: 874-23-7) is a colorless liquid with a molecular weight of approximately 136.22 g/mol. It has a melting point of -17°C and a boiling point of 178-179°C. The compound is slightly soluble in water but miscible with common organic solvents such as ethanol and acetone. It is a ketone and exhibits typical reactivity of aldehydes and ketones, including electrophilic addition and nucleophilic substitution reactions.

2-Acetylcyclohexanone (CAS: 874-23-7) is typically synthesized by the acetylation of cyclohexanol using acetic anhydride in the presence of an acid catalyst such as sulfuric acid. The reaction is conducted under reflux conditions, and the product is purified by distillation. The yield is generally around 85-90%, and the selectivity is high, ensuring a high purity of the final product.

2-Acetylcyclohexanone (CAS: 874-23-7) is used in various industries, including pharmaceuticals, where it serves as a precursor for the synthesis of certain medications. It is also utilized in the production of fragrances and flavors, as well as in the manufacturing of polymers and resins. Additionally, it plays a role in the development of sensors and semiconductors due to its reactivity and stability.

When handling 2-Acetylcyclohexanone (CAS: 874-23-7), it is essential to wear appropriate personal protective equipment (PPE), including safety goggles, gloves, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation of the vapors. Spills should be cleaned up promptly using appropriate absorbent materials, and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.