4-(Diethylamino)-2-methoxybenzaldehyde(CAS: 55586-68-0)

4-(Diethylamino)-2-methoxybenzaldehyde is a white crystalline solid with a molecular weight of approximately 212.3 g/mol. It has a solubility of about 1.5 g/100 mL in water at 25°C. This compound is moderately reactive and generally stable under normal conditions. It can form complexes with various metal ions and undergoes electrophilic aromatic substitution reactions.

4-(Diethylamino)-2-methoxybenzaldehyde can be synthesized via a condensation reaction of 2-methoxybenzaldehyde with diethylamine. Commonly, this involves refluxing the aldehyde and amine in the presence of a suitable catalyst, often sodium acetate, to achieve high selectivity and yield. The reaction proceeds with a yield of around 85-90%.

4-(Diethylamino)-2-methoxybenzaldehyde is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various drugs. It also finds applications in the production of certain dyes and pigments, as a chemical reagent, and in the development of sensors and semiconductors.

Proper handling of 4-(Diethylamino)-2-methoxybenzaldehyde requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to avoid inhalation of vapors. Spills should be cleaned up using appropriate absorbents, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.