3-Iodo-2-pyridinamine(CAS: 104830-06-0)

3-Iodo-2-pyridinamine (CAS: 104830-06-0) is a crystalline solid with a molecular weight of approximately 225.03 g/mol. It has a solubility of about 0.5 mg/mL in water and is slightly soluble in organic solvents like ethanol. The compound is known for its reactivity, particularly towards nucleophilic substitution reactions.

3-Iodo-2-pyridinamine is typically synthesized via the iodination of 2-pyridinamine using iodine in the presence of a base such as potassium carbonate. The reaction is carried out in a solvent like acetonitrile, with yields ranging from 70-80% and good selectivity towards the iodo substitution.

3-Iodo-2-pyridinamine (CAS: 104830-06-0) is used primarily in the pharmaceutical industry for the synthesis of drug candidates. It also has potential applications in polymer chemistry for functionalization and in sensor technology for detecting specific analytes.

When handling 3-Iodo-2-pyridinamine (CAS: 104830-06-0), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood due to its reactivity. Spills should be cleaned up using appropriate absorbents, and proper disposal methods should be followed. Refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.