2,2-Dimethyl-4-piperidinone(CAS: 858264-10-5)

2,2-Dimethyl-4-piperidinone is a colorless liquid with a slight odor. It has a molecular weight of 128.21 g/mol and a boiling point of 240°C. The compound is soluble in water and organic solvents. It is relatively stable but can react with strong acids and bases. It has a viscosity of 1.53 mPa·s at 25°C and a density of 1.023 g/cm³.

2,2-Dimethyl-4-piperidinone is typically synthesized by the reaction of piperidine with acetic anhydride. The process involves the condensation of piperidine with acetic anhydride in the presence of a catalyst, such as pyridine. It can also be prepared by the oxidation of 2,2-dimethyl-4-piperidinol. The yield is generally around 85-90% with good selectivity.

2,2-Dimethyl-4-piperidinone is widely used in the pharmaceutical industry for the production of drugs and intermediates. It is also used in the polymer industry as a plasticizer and in the manufacture of coatings and adhesives. Additionally, it has applications in the sensor industry and semiconductor manufacturing as a solvent and cleaner.

When handling 2,2-Dimethyl-4-piperidinone, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store the compound in a cool, well-ventilated area away from heat sources and incompatible materials. Use a fume hood during handling and disposal. In case of a spill, neutralize the compound with a base, collect the material, and dispose of it according to local regulations. Always consult the safety data sheet (SDS) for further information.