(3S)-3-Hydroxybutanenitrile(CAS: 123689-95-2)

(3S)-3-Hydroxybutanenitrile is a colorless liquid with a molecular weight of approximately 102.11 g/mol. It has a pKa of about 7.0 and is slightly soluble in water but miscible with most organic solvents. It is mildly reactive, particularly under basic conditions, and can be hydrogenated to form (3S)-3-hydroxybutane.

(3S)-3-Hydroxybutanenitrile can be synthesized via the reduction of (3S)-3-cyanobutanal with hydrogen and a catalyst such as palladium on carbon. Another method involves the reaction of 3-cyanobutanone with sodium bisulfite under basic conditions.

(3S)-3-Hydroxybutanenitrile is used in the pharmaceutical industry for intermediate synthesis, in polymer science for modifying properties of polymers, and in the chemical sensor industry for developing gas sensing devices. It also has potential applications in the semiconductor and electronics industries.

When handling (3S)-3-Hydroxybutanenitrile, it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up with appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed safety information.