2-[2-(2,3-Dihydroxypropoxy)-2-oxoethyl]-2-hydroxybutanedioic acid(CAS: 36291-32-4)

2-[2-(2,3-Dihydroxypropoxy)-2-oxoethyl]-2-hydroxybutanedioic acid is a crystalline compound with a molecular weight of approximately 320.16 g/mol. It has a solubility of about 10 g/L in water. This compound is known for its reactivity, particularly in esterification and condensation reactions. It is stable under normal conditions but should be handled with care to avoid decomposition and by-products formation.

2-[2-(2,3-Dihydroxypropoxy)-2-oxoethyl]-2-hydroxybutanedioic acid can be synthesized via condensation reactions using 2-hydroxybutanedioic acid and 2-(2,3-dihydroxypropoxy)acetic acid as the starting materials. Commonly, this process involves the use of a catalyst such as dicyclohexylcarbodiimide (DCC) and 4-(dimethylamino)pyridine (DMAP) to enhance the reaction selectivity and yield. The final product is obtained with a high yield and good purity.

2-[2-(2,3-Dihydroxypropoxy)-2-oxoethyl]-2-hydroxybutanedioic acid is widely used in the pharmaceutical industry for the synthesis of certain drug intermediates. It also finds applications in the polymer industry, where it can be used as a monomer. Additionally, it is employed in the development of sensors and as a component in semiconductor materials for specific chemical properties.

When handling 2-[2-(2,3-Dihydroxypropoxy)-2-oxoethyl]-2-hydroxybutanedioic acid, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, it should be cleaned up immediately using appropriate methods, and all waste should be disposed of in accordance with local regulations. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.