(1R)-3,8-Dimethyl-5,14-dioxatricyclo[10.2.1.0~2,6~]pentadeca-2(6),3,8,12(15)-tetraen-13-one(CAS: 728-61-0)

(1R)-3,8-Dimethyl-5,14-dioxatricyclo[10.2.1.0~2,6~]pentadeca-2(6),3,8,12(15)-tetraen-13-one is a crystalline solid with a molecular weight of approximately 250.23 g/mol. It has a low solubility in water but is soluble in organic solvents like methanol and ethanol. Chemically, it is reactive towards nucleophiles and electrophiles. It can undergo various reactions such as addition and substitution reactions.

(1R)-3,8-Dimethyl-5,14-dioxatricyclo[10.2.1.0~2,6~]pentadeca-2(6),3,8,12(15)-tetraen-13-one can be synthesized through a ring-closing metathesis (RCM) reaction of an appropriate cyclic diene derivative. The reaction typically requires a ruthenium-based catalyst and is carried out under mild conditions. The yield and selectivity of the reaction can be optimized by adjusting the catalyst concentration and reaction temperature.

(1R)-3,8-Dimethyl-5,14-dioxatricyclo[10.2.1.0~2,6~]pentadeca-2(6),3,8,12(15)-tetraen-13-one is used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the production of materials for sensors and semiconductors due to its unique chemical structure and reactive properties.

When handling (1R)-3,8-Dimethyl-5,14-dioxatricyclo[10.2.1.0~2,6~]pentadeca-2(6),3,8,12(15)-tetraen-13-one, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight. In case of a spill, it should be cleaned up using appropriate absorbents, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.