6-Mercaptonicotinic acid(CAS: 92823-43-3)

6-Mercaptonicotinic acid is a crystalline solid with a molecular weight of approximately 162.19 g/mol. It is slightly soluble in water and has a pKa of about 3.75. The acid is reactive towards nucleophiles and can undergo redox reactions.

6-Mercaptonicotinic acid can be synthesized by reacting nicotinic acid with sodium mercaptacetate. This reaction typically occurs in aqueous media with a yield of around 75%. The process may require a mild base to facilitate the reaction.

6-Mercaptonicotinic acid is used in the pharmaceutical industry for the synthesis of certain medications. It is also used in the production of sensors due to its reductive properties and in some polymer applications for its acid functionality.

When handling 6-Mercaptonicotinic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up using appropriate procedures and the material safety data sheet (MSDS) should be consulted for detailed safety information.