Sodium 18-hydroxy-18-oxoabieta-8(14),9(11),12-triene-12-sulfonate(CAS: 86408-72-2)

Sodium 18-hydroxy-18-oxoabieta-8(14),9(11),12-triene-12-sulfonate is a white crystalline solid with a molecular weight of approximately 546.47 g/mol. It is poorly soluble in water but soluble in organic solvents. Chemically, it is highly reactive with acidic and basic compounds due to its sulfonate group and carbonyl groups. Its reactivity makes it suitable for various chemical modifications and applications.

Sodium 18-hydroxy-18-oxoabieta-8(14),9(11),12-triene-12-sulfonate can be synthesized via a multi-step process involving the sulfonation of the 18-hydroxy-18-oxoabieta-8(14),9(11),12-triene followed by a deprotonation step using sodium hydride. The reaction is typically carried out in the presence of a solvent like dimethylformamide (DMF) and requires careful temperature control to ensure high yield and selectivity.

Sodium 18-hydroxy-18-oxoabieta-8(14),9(11),12-triene-12-sulfonate has applications in the pharmaceutical industry for the synthesis of complex natural products and drug intermediates. It is also used in the polymer industry for the modification of polymer chains and in the semiconductor industry for the production of advanced materials. Additionally, it can be used in sensor technology for the detection of specific analytes.

When handling Sodium 18-hydroxy-18-oxoabieta-8(14),9(11),12-triene-12-sulfonate, it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize exposure to the vapor and particles. In case of a spill, it should be cleaned up immediately with care to avoid inhalation or direct contact. For more detailed safety information, refer to the Safety Data Sheet (SDS) for this compound.