1-Methyl-3,3-diphenyltetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxazaborole(CAS: 133261-83-3)

1-Methyl-3,3-diphenyltetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxazaborole is a crystalline solid with a molecular weight of approximately 324.27 g/mol. It has low water solubility and moderate solubility in organic solvents. The compound is known for its chemical stability and reactivity in organic synthesis, particularly in reactions involving boron-containing compounds.

1-Methyl-3,3-diphenyltetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxazaborole is commonly synthesized via a multistep process involving the condensation of 1,3-diphenyltetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxazaborole with methyl bromide. The synthesis typically requires the use of catalytic amounts of palladium(II) acetate and triphenylphosphine to achieve good yield and selectivity.

1-Methyl-3,3-diphenyltetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxazaborole is primarily used in the pharmaceutical industry for developing novel drug candidates. It is also explored in the polymer industry for its potential as a monomer, and in the semiconductor industry for its use in organic electronics and as a dopant.

When handling 1-Methyl-3,3-diphenyltetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxazaborole, it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for specific disposal instructions and safety measures.