1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazine(CAS: 401566-79-8)

1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazine has a solid crystalline form. Its molecular weight is approximately 324.34 g/mol. It is slightly soluble in water but soluble in organic solvents such as ethanol and dichloromethane. Chemically, it is stable under normal conditions but can react with strong acids or bases. It is not flammable and has a melting point around 180-185°C.

1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazine is typically synthesized via a multistep process involving the condensation of 3-methyl-1-phenyl-1H-pyrazole and piperazine. Commonly, this is achieved using reagents like N,N'-carbonyldiimidazole as a coupling agent, with yields around 70-80%. The process requires careful temperature control and the use of appropriate catalysts to ensure high selectivity and purity.

1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazine is used in the pharmaceutical industry for its potential as a bioactive compound. It also finds applications in the polymer industry for its structural features and in the sensor industry due to its chemical reactivity. Additionally, it has potential uses in semiconductor manufacturing processes as a dopant or additive.

When handling 1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl)piperazine, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate procedures and waste should be disposed of according to local regulations. Always refer to the safety data sheet (SDS) for detailed handling instructions.