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5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-4H-chromen-4-one(CAS: 855-96-9)

5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-4H-chromen-4-one
CAS Number

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Basic Information

Molecular Formula
C18H16O7
Molecular Weight
344.32 g/mol
Physical State
Yellow powder

Physical Properties

Melting Point
194-196°C
Boiling Point
587℃ at 760 mmHg
Density
1.4±0.1 g/cm3
Flash Point
216.0±23.6 °C
Water Solubility
Insoluble in water. Soluble in chloroform and methanol.

Chemical Identifiers

SMILES
COc1ccc(cc1O)c2cc(=O)c3c(o2)cc(c(c3O)OC)OC
InChIKey
KLAOKWJLUQKWIF-UHFFFAOYSA-N

Database References

MDL Number
MFCD00016929
Beilstein Registry Number
1355109

FAQ

5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-4H-chromen-4-one has a crystalline form and a molecular weight of approximately 402.3 g/mol. It is poorly soluble in water but soluble in organic solvents like ethanol and acetone. This compound exhibits moderate reactivity due to its chromone structure, making it susceptible to oxidation. It is stable under normal laboratory conditions but should be stored in a cool, dark place to prevent photodegradation.
5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-4H-chromen-4-one can be synthesized via a multi-step process involving the condensation of 3-hydroxy-4-methoxyphenol with an appropriate chromone derivative. Commonly, this is achieved using an esterification followed by a coupling reaction. The reaction typically requires a base like sodium hydroxide and is conducted in an aqueous-organic solvent mixture. Yield and selectivity are generally good, and the method is reproducible under standard conditions.
5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-4H-chromen-4-one is used in various industries. It is a key intermediate in the synthesis of certain pharmaceuticals due to its pharmacological properties. It is also used in the production of polymers for its structural integrity and in the development of sensors and semiconductors for its electronic properties. Its versatility makes it a valuable compound in multiple sectors.
When handling 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-4H-chromen-4-one, it is essential to use appropriate personal protective equipment (PPE), including gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation of fumes. Spills should be cleaned up using appropriate absorbent materials, and the area should be thoroughly washed. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

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