3-Benzyl-3H-purin-6-amine(CAS: 7280-81-1)

3-Benzyl-3H-purin-6-amine (CAS: 7280-81-1) is a crystalline solid with a molecular weight of approximately 229.27 g/mol. It is soluble in organic solvents such as methanol and dimethylformamide. This compound exhibits moderate reactivity, particularly towards nucleophilic substitution reactions. It has a pKa of about 8.5.

3-Benzyl-3H-purin-6-amine (CAS: 7280-81-1) is typically synthesized through the reaction of 6-aminopurine with benzyl chloride in the presence of a base like sodium hydride. The yield is generally around 70-80%, and the reaction is carried out in a solvent such as dimethylformamide (DMF).

3-Benzyl-3H-purin-6-amine (CAS: 7280-81-1) is primarily used in the pharmaceutical industry for the development of antiviral and anticancer drugs. It is also used in the synthesis of certain polymers and sensors due to its unique chemical structure.

When handling 3-Benzyl-3H-purin-6-amine (CAS: 7280-81-1), it is important to use appropriate personal protective equipment (PPE) such as gloves and laboratory coats. Work should be conducted in a well-ventilated area or fume hood. In case of a spill, it should be immediately cleaned up using appropriate absorbent materials, and the area should be thoroughly rinsed. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.