(S)-Methyl 3-hydroxytetradecanoate(CAS: 76835-67-1)

(S)-Methyl 3-hydroxytetradecanoate is a white crystalline solid with a molecular weight of approximately 250.38 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. Chemically, it is relatively stable but can undergo ester hydrolysis in the presence of acids or bases. It has a melting point of about 65-67°C and a boiling point of approximately 285°C.

The synthesis of (S)-Methyl 3-hydroxytetradecanoate typically involves the reaction of 3-hydroxytetradecanoic acid with methyl alcohol in the presence of a strong acid catalyst, such as hydrochloric acid, at a temperature range of 60-80°C. The reaction proceeds with high selectivity towards the (S) configuration, and the yield can reach up to 90% under optimized conditions.

(S)-Methyl 3-hydroxytetradecanoate finds applications in the pharmaceutical industry as a precursor for the synthesis of bioactive compounds. It is also used in the polymer industry as an additive to improve the mechanical properties of polymers. Additionally, it has potential applications in the production of sensors and semiconductors due to its unique physical and chemical properties.

When handling (S)-Methyl 3-hydroxytetradecanoate, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or under a fume hood to minimize exposure. In case of a spill, wipe up with absorbent material and dispose of it according to local regulations. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.