(2-Methoxyphenyl)boronic acid(CAS: 5720-06-9)

(2-Methoxyphenyl)boronic acid is a white crystalline solid with a molecular weight of approximately 227.24 g/mol. It is slightly soluble in water but soluble in organic solvents such as ethanol and chloroform. Chemically, it is a Lewis acid and shows limited reactivity under standard conditions, but it can participate in boron-mediated reactions with good selectivity and yield.

(2-Methoxyphenyl)boronic acid is commonly synthesized via the Stille coupling reaction, where 2-methoxyphenyl bromide reacts with triphenylphosphine in the presence of a palladium catalyst. This method provides good yields and high selectivity, making it a reliable route for large-scale production.

(2-Methoxyphenyl)boronic acid is used in various industries, particularly in pharmaceuticals for the synthesis of medicinal compounds, and in materials science for the development of new polymers and sensors. It also finds applications in semiconductor manufacturing for the production of advanced electronic devices.

When handling (2-Methoxyphenyl)boronic acid, it is important to use appropriate personal protective equipment (PPE) such as gloves and safety goggles. Store it in a cool, well-ventilated area away from direct sunlight and heat sources. In case of a spill, immediately clean up using appropriate absorbent materials and follow standard laboratory safety procedures. Refer to the Safety Data Sheet (SDS) for specific handling instructions and emergency response details.