2-[(3-Amino-4-methoxyphenyl)amino]ethanol(CAS: 83763-47-7)

2-[(3-Amino-4-methoxyphenyl)amino]ethanol (CAS: 83763-47-7) is a crystalline solid with a molecular weight of approximately 224.27 g/mol. It has a solubility of about 6 g/L in water and exhibits basic reactivity due to the amino group. This compound is stable under normal conditions but requires protection from strong acids and bases.

2-[(3-Amino-4-methoxyphenyl)amino]ethanol can be synthesized via the reaction of 4-methoxy-3-nitroaniline with ethylene diamine followed by reduction and basic workup. Common catalysts include zinc powder and aqueous sodium hydroxide. The reaction provides a yield of around 85%, and it is selective and efficient.

2-[(3-Amino-4-methoxyphenyl)amino]ethanol (CAS: 83763-47-7) is primarily used in pharmaceuticals for the synthesis of certain drug molecules. It also finds applications in the production of dyes, as a precursor in polymer chemistry, and in the development of sensors and semiconductors due to its functional groups.

When handling 2-[(3-Amino-4-methoxyphenyl)amino]ethanol (CAS: 83763-47-7), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Operations should be conducted in a fume hood to minimize inhalation risk. Proper spill cleanup procedures should be followed, and the material safety data sheet (MSDS) should be consulted for detailed information on handling and disposal.